Benign prostatic hyperplasia and prostate-specific antigen

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Prostate-specific antigen density: correlation with histological diagnosis of prostate cancer, benign prostatic hyperplasia and prostatitis.

OBJECTIVE To assess the additional value of prostate-specific antigen density in the diagnosis of prostate cancer in patients who undergo prostate biopsies. PATIENTS AND METHODS The study comprised 376 patients with symptoms of prostatism who were undergoing prostate biopsy. Digital rectal examination (DRE) and transrectal ultrasonography (TRUS) were performed and the prostate specific antige...

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Relationship of age, prostate-specific antigen, and prostate volume in Indonesian men with benign prostatic hyperplasia

BACKGROUND To investigate the relationship between age, prostate specific antigen (PSA), and prostate volume (PV) in Indonesian men with histologically proven benign prostatic hyperplasia. METHODS Data were generated from our BPH database from June 1994 until December 2013. Subjects were men with a minimum age of 40 years with chief complaint of LUTS or urinary retention, diagnosed with BPH. ...

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Study of Correlation between Prostate Specific Antigen and Matrix Metalloproteinase-2 Activity in Benign and Malignant Prostate Hyperplasia

There are emerging data on novel tumor markers such as matrix metalloproteinase-2 (MMP-2 or gelatinase-A), which play a key role in tissue invasion and metastasis. We designed an investigation to assess the usefulness of MMP-2 activity as compared to prostate specific antigen (PSA) in cancer staging process. We have analyzed the circulating form of MMP-2 in serum samples of patients suffering f...

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Variations of Prostate-Specific Antigen and Cytokines in Patients with Benign Prostatic Hyperplasia

The etiology of benign prostatic hyperplasia (BPH) is still obscure. Data supporting an interaction connecting prostate hyperplasia and immune disregulation is accumulating. Serum levels of pro-inflammatory and antiinflammatory cytokines measured by enzyme-linked immunosorbent assay in 3 groups of patients with BPH. The groups included 12 men who had mean prostate specific antigen (PSA) serum c...

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Benign prostatic hyperplasia and prostate cancer.

Benign prostatic hyperplasia refers to an anatomic diagnosis, yet in practice it is typically diagnosed clinically on the basis of lower urinary tract symptoms and prostatic enlargement detected on manual rectal examination or transrectal ultrasonography (1). Over the past decade, since benign prostatic hyperplasia (2) and prostate cancer (3) were reviewed in this Journal, there has been a prol...

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ژورنال

عنوان ژورنال: Military Medical and Pharmaceutical Journal of Serbia

سال: 2015

ISSN: 0042-8450,2406-0720

DOI: 10.2298/vsp1505447p